Resolving Resolution
نویسندگان
چکیده
منابع مشابه
Resolving the resolution of array CGH.
Many recent technologies have been designed to supplant conventional metaphase CGH technology with the goal of refining the description of segmental copy number status throughout the genome. However, the emergence of new technologies has led to confusion as to how to describe adequately the capabilities of each array platform. The design of a CGH array can incorporate a uniform or a highly vari...
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Regulation of microRNA (miRNA) localization and stability is critical for their extensive cytoplasmic RNA silencing activity and emerging nuclear functions. Here, we have developed single-molecule fluorescence-based tools to assess the subcellular trafficking, integrity, and activity of miRNAs. We find that seed-matched RNA targets protect miRNAs against degradation and enhance their nuclear re...
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Massive star clusters observed in galaxy mergers are often suggested to be progenitors of globular clusters. To study this hypothesis, we performed the highest resolution simulation of a gas-rich galaxy merger so far. The formation of massive star clusters of 10 to 10 M⊙, triggered by the galaxy interaction, is directly resolved in this model. We show that these clusters are tightly bound struc...
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ژورنال
عنوان ژورنال: Information Display
سال: 2011
ISSN: 0362-0972
DOI: 10.1002/j.2637-496x.2011.tb00419.x